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Cytoprotection of Cecropia obtusifolia Bertol (Cecropiaceae) extract on the normal adherent cell line of human fibroblasts Hs68

By
Edelia Claudina Villarreal-Ibarra ,
Edelia Claudina Villarreal-Ibarra

Universidad Popular de la Chontalpa. Tabasco, México

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Catalina Rivas-Morales ,
Catalina Rivas-Morales

Universidad Autónoma de Nuevo León. Nuevo León, México

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Catalina Leos-Rivas ,
Catalina Leos-Rivas

Universidad Autónoma de Nuevo León. Nuevo León, México

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Benigno Rivera Hernández ,
Benigno Rivera Hernández

Universidad Popular de la Chontalpa. Tabasco, México

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Damianys Almenares López ,
Damianys Almenares López

Universidad Autónoma de Nuevo León. Nuevo León, México

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Abstract

The study focuses on the therapeutic action of medicinal plants used in the treatment of chronic degenerative diseases. The ethanolic extract of the Mexican species Cecropia obtusifolia Bertol, traditionally used for diabetes, was evaluated. The cytoprotective effect was determined on the normal adherent human fibroblast cell line Hs68, and its toxicity was assessed on Artemia salina. The cytoprotective effect was determined using the neutral red (NR) assay, demonstrating a viability of 98%, indicating a very low cytotoxic effect and no toxicity on A. salina. These assays have been routinely employed as screening methods for natural extracts and pure compounds with potential therapeutic effects against cancer.

How to Cite

1.
Villarreal-Ibarra EC, Rivas-Morales C, Leos-Rivas C, Rivera Hernández B, Almenares López D. Cytoprotection of Cecropia obtusifolia Bertol (Cecropiaceae) extract on the normal adherent cell line of human fibroblasts Hs68 . Salud, Ciencia y Tecnología - Serie de Conferencias [Internet]. 2024 May 9 [cited 2024 May 21];3:754. Available from: https://conferencias.saludcyt.ar/index.php/sctconf/article/view/754

The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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