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Published March 6, 2024

Salud, Ciencia y Tecnología - Serie de Conferencias

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Editorial Salud, Ciencia y Tecnología

Title:

Salud, Ciencia y Tecnología - Serie de Conferencias

ISSN-L: 2953-4860

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2024-06-14 Original
Examining burnout and stress among healthcare professionals during and post COVID-19 lockdown: A comparative analysis

By Priya Sethuraman, Arasuraja Ganesan, Satish Radhakrishnan

Purpose: The purpose of this paper is to conduct a comprehensive comparative analysis focusing on burnout and stress experienced by healthcare professionals during and after the COVID-19 lockdown. The COVID-19 pandemic presented an unprecedented challenge for society, particularly for healthcare professionals who faced extended hours, direct exposure to the virus, and substantial stress and burnout. This analysis aims to shed light on the experiences of healthcare professionals during this challenging period and its aftermath, highlighting the need for proactive measures by policymakers and healthcare organizations to support mental health and well-being.

Methods: The research employs a comparative analysis approach to assess the levels of burnout and stress among healthcare professionals during and post the COVID-19 lockdown. It likely involves surveying healthcare professionals, collecting data on their experiences, and analyzing trends and patterns over time. The methodology may also include qualitative interviews or focus groups to gain deeper insights into the factors contributing to stress and burnout among healthcare professionals.

Results and Discussion: The results of the study are expected to reveal the extent of burnout and stress experienced by healthcare professionals during and after the COVID-19 lockdown. This section will discuss the key findings, highlighting any significant differences in stress levels between the two periods and identifying factors contributing to burnout among healthcare professionals. Possible discussions may explore the impact of workload, lack of resources, and personal challenges on mental health and well-being, as well as the effectiveness of existing support systems and interventions.

Implications of the Research: The implications of this research are far-reaching, offering valuable insights for policymakers, healthcare organizations, and healthcare professionals themselves. By understanding the unique challenges faced by healthcare professionals during the COVID-19 pandemic and its aftermath, policymakers can develop proactive measures to support mental health and well-being in future public health crises. Healthcare organizations can use the findings to tailor strategies and interventions aimed at reducing burnout and stress among their workforce, ultimately improving patient care and overall organizational performance.

Originality/Value: This research contributes to the existing body of knowledge on the impact of the COVID-19 pandemic on healthcare professionals' mental health and well-being. By conducting a comparative analysis, this study offers unique insights into the dynamics of stress and burnout before, during, and after the COVID-19 lockdown. The findings have significant implications for practice, policy, and future research in the field of healthcare workforce management and public health emergency preparedness.

2024-05-31 Review
Use of the Zebrafish Model as a Tool to Evaluate the Anti- Inflammatory and Antioxidant Activity of Molecules. Literature Review

By Cristina Arteaga, Luis Felipe Contreras, Ruth Borja, Carolina Campoverde, Alberto Bustillos

Introduction: The evaluation of antioxidant and anti-inflammatory properties in biological models is crucial for advancing pharmacological research. The zebrafish model (Danio rerio) is increasingly used due to its genetic similarity to humans and its translational relevance in drug discovery. This work synthesizes the existing literature on the use of zebrafish as a model for testing the efficacy of various substances with antioxidant and anti-inflammatory properties.
Methods: A comprehensive literature review was conducted using the Web of Science database. Search terms included "zebra fish," "antioxidant," "anti-inflammatory," "model," and "Danio rerio." Out of fifty articles initially reviewed, thirty-three met the inclusion criteria and were analyzed further. These articles were categorized based on the source of the substances tested, including plant extracts, compounds extracted from plants, chemical compounds, and other sources.
Results: The reviewed studies utilized a variety of methods to assess the antioxidant and anti-inflammatory effects in zebrafish, including observational assays and molecular techniques. The substances tested were derived mainly from plant extracts and chemical compounds. The analysis highlights significant variability in methodology and outcomes, reflecting both the versatility and the challenges of using zebrafish in this type of research.
Conclusions: The zebrafish model is a valuable tool for studying antioxidant and anti-inflammatory properties, offering several advantages including genetic tractability, cost-effectiveness, and the ability to observe phenotypic changes in vivo. However, standardization of methodologies and a deeper understanding of the model’s limitations are essential for maximizing its utility in biomedical research. This review provides a foundation for future studies aiming to optimize zebrafish use in evaluating therapeutic agents.

2024-06-22 Systematic reviews or meta-analyses
Usefulness of Vitamin C in critically ill patients: A systematic review

By Karoline Sousa do Nascimento, Fernando Lipoyestky

Abstract
Background: Vitamin C, also known as ascorbic acid, is an essential micronutrient that plays a key role in fighting systemic inflammation in critically ill patients. Low levels of this vitamin are common in critically ill individuals due to increased oxidative stress. The objective of this study is to investigate and evaluate the use of vitamin C in critically ill patients admitted to intensive care units, with the purpose of identifying its advantages and limitations, and determining its effectiveness in reducing mortality in this group of patients. Material and methods: The present study is a systematic review; previously published articles were searched in the PubMed database. The research was carried out at the university level. 14 results were obtained. Results: Results from clinical and observational studies have been controversial, but some reports suggest improvements in organ function, shorter ICU stays, and reduced mortality in certain patient groups. Other studies did not show a significant change in mortality to justify the use of vitamin C therapy. Conclusion: Controversy regarding clinical results persists; monotherapy with high doses of vitamin C presents a biologically acceptable justification. While we wait for more results, it is important to ensure that critically ill patients receive the recommended dose of vitamin C to keep their immune and metabolic function optimized and ensure daily intake for healthy people.

2024-03-06 Case Report
Bone involvement as a presentation of breast cancer metastasis

By Ronald Vladimir Revelo Mera , Bolívar Alfredo Potes Berzosa, Alejandro Julián Terreros Bueno, Geovanna Paola Jaramillo Calderón, Rómulo Daniel Vargas Sánchez

Occult breast cancer is that condition that manifests as a metastatic axillary lymph node, without clinical or radiological manifestation of a primary breast tumor. It is a rare condition and was previously referred to only as non-palpable lesions. On the other hand, metastasis is the process through which the spread of a primary cancer focus to another organ occurs. This spread is carried out through the blood or lymphatic route. The organs that cause metastasis to bones are the breast, lung and prostate, in male patients. Currently, there is a high percentage of published clinical cases referring to bone involvement of breast origin and it is for this reason and the form of presentation, added The metastatic aggressiveness that we were able to observe is that in this article we detail the clinical case of a female patient with metastasis of occult breast cancer, where several organs were affected

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