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Epidermal necrolysis in a renal transplanted patient

By
Yangel Fuentes Milián ,
Yangel Fuentes Milián

Universidad de Ciencias Médicas de Pinar del Río. Pinar del Río, Cuba.

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Víctor Manuel Hernández Valdés ,
Víctor Manuel Hernández Valdés

Universidad de Ciencias Médicas de Pinar del Río. Hospital General Docente Abel Santamaría Cuadrado. Pinar del Río, Cuba.

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Maydelis Crusa Lorenzo ,
Maydelis Crusa Lorenzo

Universidad de Ciencias Médicas de Pinar del Río. Hospital General Docente Abel Santamaría Cuadrado. Pinar del Río, Cuba.

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Abstract

Introduction: epidermal necrolysis is a mucocutaneous hypersensitivity reaction induced mainly by drugs and infections. It includes two conditions that differ in the percentage of affected skin: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

Case presentation: 52-year-old female patient, white skin, with personal pathological history of mesangial glomerulonephritis (IgA) and secondary chronic renal failure, nephrotransplanted since 34 years ago, with functional graft under immunosuppressive treatment. She was referred from her health area to the Nephrology Service of the General Teaching Hospital "Abel Santamaría Cuadrado" for presenting evolving herpes zoster, with bacterial superinfection in the right hemithorax, accompanied by intense pain, fever up to 39 °C, general malaise and disseminated dermatosis. 

Conclusions: the patient presented a picture of epidermal necrolysis related to the immunosuppressive state after renal transplantation as a complication of herpes zoster.  The diagnosis was based on clinical findings and through timely treatment, a satisfactory discharge was possible.

How to Cite

1.
Fuentes Milián Y, Hernández Valdés VM, Crusa Lorenzo M. Epidermal necrolysis in a renal transplanted patient. Salud, Ciencia y Tecnología - Serie de Conferencias [Internet]. 2022 Dec. 11 [cited 2024 Jun. 29];1:293. Available from: https://conferencias.saludcyt.ar/index.php/sctconf/article/view/293

The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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