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Systematic reviews or meta-analyses

Emergency Delirium Prevention with Dexmedetomidine in Pediatrics

By
Gabrielly Araujo Barreto ,
Gabrielly Araujo Barreto

Universidad Abierta Interamericana. Facultad de Medicina y Ciencias de la Salud. Ciudad Autónoma de Buenos Aires, Argentina.

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Javier González-Argote ,
Javier González-Argote

Fundación Salud, Ciencia y Tecnología. Ciudad Autónoma de Buenos Aires, Argentina.

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Abstract

Introduction: Prevention of emergency delirium with dexmedetomidine in pediatric patients is a topic of growing interest in medical practice and clinical research. Emergency delirium, also known as pediatric intensive care unit (PICU) delirium syndrome, is a severe neuropsychiatric disorder affecting critically ill children and adolescents. Objectives: To comprehensively analyze the available scientific literature in order to evaluate the effectiveness and safety of dexmedetomidine as a pharmacological agent in the prevention of emergency delirium in pediatric patients. Material and methods: A Systematic Review of the literature will be carried out in accordance with PRISMA guidelines. The units of analysis will be the abstracts and full text of papers with randomized clinical trial design or prospective or retrospective cohort, published in Scopus, Web of Science and Pubmed, without temporal restriction. Results: The systematic review indicates that dexmedetomidine shows promise in reducing the incidence of postoperative delirium, emergence delirium, and pain in various surgical populations. These findings have significant clinical implications, especially for elderly patients and children undergoing specific procedures. The safety profile of dexmedetomidine was generally acceptable, with no major adverse events reported. In conclusion, while the systematic review suggests that dexmedetomidine may offer benefits in preventing postoperative delirium and improving perioperative outcomes, further research is needed to establish the optimal dose, refine assessment methods, and explore its long-term effects. Dexmedetomidine promises to be a valuable tool in pediatric and geriatric surgical settings, with the potential to improve patient care and recovery.

How to Cite

1.
Araujo Barreto G, González-Argote J. Emergency Delirium Prevention with Dexmedetomidine in Pediatrics. Salud, Ciencia y Tecnología - Serie de Conferencias [Internet]. 2023 Sep. 18 [cited 2024 Jun. 26];2:320. Available from: https://conferencias.saludcyt.ar/index.php/sctconf/article/view/320

The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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