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Salud, Ciencia y Tecnología Metaverse Basic and Applied Research Data & Metadata Interdisciplinary Rehabilitation Salud, Ciencia y Tecnología - Serie de Conferencias Community and Interculturality in Dialogue Seminars in Medical Writing and Education Health Leadership and Quality of Life Gamification and Augmented Reality Southern perspective / Perspectiva austral
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Original
Published: 2023-12-20
DOI: https://doi.org/10.56294/sctconf2023769

New perspectives in the treatment of heart failure: The role of SGLT2 inhibitors

By
Riber Fabián Donoso Noroña ,
Riber Fabián Donoso Noroña

Universidad Regional Autónoma de Los Andes. Ambato, Ecuador

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Nairovys Gómez Martínez ,
Nairovys Gómez Martínez

Universidad Regional Autónoma de Los Andes. Ambato, Ecuador

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Adisnay Rodríguez Plasencia ,
Adisnay Rodríguez Plasencia

Universidad Regional Autónoma de Los Andes. Ambato, Ecuador

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Abstract

Heart failure (HF) has been a prevalent chronic disease globally and one of the main causes of mortality historically. A recent study assessed the impact of sodium-glucose cotransporter 2 inhibitors (SGLT2 inhibitors) on the management of HF. It focused on improving health outcomes and the quality of life of patients. The methodology included a systematic review of clinical and observational trials that compared SGLT2 inhibitors with standard treatments and placebos. The efficacy of SGLT2 inhibitors was examined across various patient subgroups, taking into account variables such as renal and cardiovascular function, vascular resistance, and neurohormonal mechanisms. The results showed that SGLT2 inhibitors significantly improved cardiac and renal function. They also reduced mortality and hospitalizations associated with HF. These benefits were observed in both patients with type 2 diabetes and those without this condition. In conclusion, the study confirmed that SGLT2 inhibitors are a valuable therapeutic option for patients with HF. It highlighted the need to include them in treatment strategies and emphasized the importance of expanding research to better understand the mechanisms, efficacy, and safety of SGLT2 inhibitors in HF, thereby guiding future health policies

Keywords:

Quality of life,
vascular resistance,
health policies,

How to Cite

1.
Donoso Noroña RF, Gómez Martínez N, Rodríguez Plasencia A. New perspectives in the treatment of heart failure: The role of SGLT2 inhibitors. Salud, Ciencia y Tecnología - Serie de Conferencias [Internet]. 2023 Dec. 20 [cited 2024 Jul. 5];2:769. Available from: https://conferencias.saludcyt.ar/index.php/sctconf/article/view/769

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The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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IV Jornadas de Fundamentos y Aplicaciones de la Interdisciplina (JFAI2023)
Vol. 2 (2023)
See full issue

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