University of Medical Sciences of Pinar del Río. Faculty of Medicine Dr. Ernesto Che Guevara de la Serna. 1st of January Polyclinic. Pinar del Río, Cuba.
University of Medical Sciences of Pinar del Río. Faculty of Medicine Dr. Ernesto Che Guevara de la Serna. Modesto Gómez Rubio Polyclinic. Pinar del Río, Cuba.
Introduction: Sepsis is a syndrome of life-threatening physiological, pathological and biochemical abnormalities associated with infection. These abnormalities are secondary to a disproportionate immune response to infection, which ultimately damages the patient's own tissues and organs and leads to multiorgan dysfunction.
Objective: To describe the risk factors, clinical manifestations, treatment and diagnosis of neonatal sepsis.
Methods: The following databases were consulted: SciELO, DIALNET, Healthline, MEDLINE and PubMed. Articles in Spanish and English were retrieved and 14 references were selected.
Development: Neonatal sepsis syndrome is one of the main causes of mortality in children. Daily practice in pediatric and neonatal ICUs shows that the signs and symptoms of sepsis are highly variable, depending on the age of the patients; the younger the child, the more unspecific the clinical manifestations. Diagnosis in early stages, according to the above definitions, guarantees recovery with adequate therapeutics.
Conclusions: Despite the numerous investigations carried out on sepsis, the high morbidity and mortality due to its cause reveal insufficient knowledge about it, which in many cases prevents timely identification of its clinical manifestations and jeopardizes the survival of hospitalized children.
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